LINC00459

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00459 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated LINC00459 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00459 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00459 expression acts as an unfavorable survival marker.

KIRC, BRCA, and COAD are the cancer types where LINC00459 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIV0.3490.659.001135view →
BRCAOSTertileIII,IV0.1060.906<.00196view →
COADDFSTertileIII,IV0.0280.668<.00154view →
BLCADFSTertileIV0.0840.480<.00148view →
KICHOSTertileAll0.1550.926<.00148view →
THYMDFSTertileAll0.3800.897<.00136view →
ACCOSTertileAll0.1330.686.00436view →
LUADOSTertileIII,IV0.0570.680<.00136view →
READOSTertileAll0.1830.828<.00136view →
SARCOSTertileAll0.2500.738<.00130view →
UCECOSTertileIV0.3390.762.04318view →
UCSDFSTertileAll0.1650.536.00318view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration