LINC00458

Across TCGA patient cohorts, LINC00458 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,417 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00458-associated GO terms across cancer lineages are Regulation of mitochondrial translation, Mitochondrial translation, and Regulation of cellular response to transforming growth factor beta stimulus. Each is linked with LINC00458 in more than 7 cancer types. Because this analysis shows association rather than direction, both LINC00458-to-partner and partner-to-LINC00458 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial translation grouped by LINC00458-low versus LINC00458-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00458→partner) and Y-score (partner→LINC00458) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of mitochondrial translation →	+0.063	+0.035	<.001	<.001	3	8
STAD	Mitochondrial translation →	+0.080	+0.041	<.001	<.001	3	7
STAD	Regulation of cellular response to transforming growth factor beta stimulus →	+0.053	+0.033	<.001	<.001	3	7
STAD	Energy reserve metabolic process →	+0.042	+0.031	<.001	<.001	3	7
STAD	Response to toxic substance →	+0.043	+0.032	<.001	<.001	3	7
STAD	Mitochondrial gene expression →	+0.075	+0.039	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,417 associations by consensus.

Regulation of mitochondrial translation by LINC00458 expression — STAD

Explore this box plot interactively →