Across TCGA patient cohorts, LINC00457 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,105 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LINC00457-associated proteins across cancer lineages are NBEA, DNMT1, and NAA50. Each is linked with LINC00457 in more than 3 cancer types. Because this analysis shows association rather than direction, both LINC00457-to-partner and partner-to-LINC00457 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00457→partner) and Y-score (partner→LINC00457) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NBEA →	+0.506	+0.359	<.001	<.001	3	4
BRCA	DNMT1 →	-0.411	-0.282	<.001	.003	3	3
BRCA	NAA50 →	-0.308	-0.199	<.001	.001	3	3
BRCA	RBM17 →	-0.208	-0.254	<.001	<.001	3	2
BRCA	RPUSD3 →	-0.412	-0.162	<.001	.009	3	2
GBM	HINT3 →	+0.401	+0.143	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,105 associations by consensus.

Exploration

LINC00457 survival (RNA) · tumor vs normal (RNA) · all LINC00457 data types