LINC00446

Across TCGA patient cohorts, LINC00446 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,173 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00446-associated GO terms across cancer lineages are Response to alcohol, Cellular ketone metabolic process, and Cellular respiration. Each is linked with LINC00446 in more than 8 cancer types. Because this analysis shows association rather than direction, both LINC00446-to-partner and partner-to-LINC00446 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to alcohol grouped by LINC00446-low versus LINC00446-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00446→partner) and Y-score (partner→LINC00446) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to alcohol →	+0.072	+0.090	<.001	<.001	3	9
STAD	Cellular ketone metabolic process →	+0.066	+0.101	<.001	<.001	3	8
STAD	Cellular respiration →	+0.117	+0.111	<.001	<.001	3	8
STAD	Cellular response to toxic substance →	+0.076	+0.100	<.001	<.001	3	8
STAD	Regulation of receptor-mediated endocytosis →	+0.078	+0.091	<.001	<.001	3	8
STAD	Nucleoside phosphate biosynthetic process →	+0.094	+0.102	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,173 associations by consensus.

Response to alcohol by LINC00446 expression — STAD

Explore this box plot interactively →