Q-omics provides the consensus-scored LINC00446 profile across patient tissues and cancer cell-line models. LINC00446 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in ACC. Additionally, LINC00446 RNA expression shows 6,776 significant gene co-expression associations, with the highest sampling consensus in LUAD. Together, these results highlight ACC, and LUAD as cancer lineages where LINC00446 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes LINC00446 survival associations across molecular data types. LINC00446 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

LINC00446 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	ACC (135)	view →

This table ranks reproducible LINC00446 RNA expression–survival associations across cancer types. High LINC00446 expression shows unfavorable associations in ACC, BRCA, ESCA, UCEC, SKCM and CESC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for LINC00446 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.010	0.667	<.001	135	view →
BRCA	OS	Tertile	II,III,IV	0.642	0.915	<.001	54	view →
ESCA	OS	Tertile	II,III,IV	0.540	0.727	.025	30	view →
UCEC	OS	Tertile	All	0.390	0.690	.001	30	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	24	view →
CESC	DFS	Tertile	II,III,IV	0.146	0.705	.010	18	view →

Pink = unfavorable, green = favorable. all 10 lineages →

LINC00446-ACC (DFS)

Kaplan–Meier survival curve for LINC00446 RNA expression in ACC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with LINC00446 in patient tissues and cancer cell lines. In patient samples, LINC00446 shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	6,776	LUAD (3374)	view →
Function (RNA)	6,173	STAD (5833)	view →