LINC00421

Across TCGA patient cohorts, LINC00421 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,616 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00421-associated GO terms across cancer lineages are Calcium ion transmembrane import into cytosol, Protein N-linked glycosylation via asparagine, and Leukocyte apoptotic process. Each is linked with LINC00421 in more than 9 cancer types. Because this analysis shows association rather than direction, both LINC00421-to-partner and partner-to-LINC00421 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion transmembrane import into cytosol grouped by LINC00421-low versus LINC00421-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00421→partner) and Y-score (partner→LINC00421) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Calcium ion transmembrane import into cytosol →	+0.035	+0.042	<.001	<.001	3	10
STAD	Protein N-linked glycosylation via asparagine →	+0.075	+0.049	<.001	<.001	3	9
STAD	Leukocyte apoptotic process →	+0.075	+0.050	<.001	<.001	3	9
STAD	Negative regulation of cell-cell adhesion →	+0.063	+0.056	<.001	<.001	3	8
PAAD	Mature B cell differentiation →	+0.065	+0.014	<.001	.001	3	8
STAD	CD4-positive, alpha-beta T cell activation →	+0.065	+0.049	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,616 associations by consensus.

Calcium ion transmembrane import into cytosol by LINC00421 expression — STAD

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