LINC00421

Across TCGA patient cohorts, LINC00421 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00421-associated genes across cancer lineages are MIR4476 and MIR412. Each is linked with LINC00421 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00421-to-partner and partner-to-LINC00421 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4476 grouped by LINC00421-low versus LINC00421-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00421→partner) and Y-score (partner→LINC00421) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4476 →	+0.736	+8.066	<.001	.007	3	1
UCEC	MIR412 →	+0.621	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIR4476 by LINC00421 expression — UCEC

Explore this box plot interactively →