LINC00404

Across TCGA pan-cancer cohorts, LINC00404 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC00404 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC00404 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00404 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PAAD show a favorable association.

UVM, KICH, and KIRP are the cancer types where LINC00404 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.398	0.759	<.001	148	view →
KICH	DFS	Tertile	All	0.026	0.904	<.001	99	view →
KIRP	DFS	Tertile	All	0.598	0.926	<.001	78	view →
THCA	OS	Tertile	III,IV	0.490	0.864	<.001	75	view →
LUAD	DFS	Tertile	III,IV	0.841	0.597	.007	63	view →
SKCM	OS	Tertile	All	0.690	0.810	.001	42	view →
ACC	DFS	Tertile	All	0.180	0.610	.004	42	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
KIRC	OS	Tertile	All	0.683	0.810	.019	36	view →
PAAD	OS	Tertile	All	0.690	0.435	.005	32	view →
OV	OS	Tertile	IV	0.753	0.335	.013	24	view →
COAD	OS	Tertile	All	0.412	0.627	.001	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC00404–UVM (DFS)

Open the UVM breakdown →