LINC00404

Across TCGA pan-cancer cohorts, LINC00404 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC00404’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC00404 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00404 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA, COAD, and ESCA are the cancer types where LINC00404 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00404 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.048	<.001	4	view →
COAD	Male	II,III,IV	−0.409	<.001	2	view →
ESCA	Female	All	−0.356	.039	2	view →
LUSC	All	All	+0.426	.024	1	view →
STAD	Male	All	−0.247	.016	1	view →
LUAD	Male	All	+0.089	.049	1	view →
KIRC	All	All	−0.007	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC00404–THCA

Open the THCA breakdown →