LINC00399

Across TCGA pan-cancer cohorts, LINC00399 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LINC00399 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher LINC00399 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00399 expression acts as an unfavorable survival marker, although some lineages such as LIHC and LAML show a favorable association.

LUSC, LIHC, and LAML are the cancer types where LINC00399 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.246	0.428	.007	45	view →
LIHC	DFS	Quartile	III,IV	0.435	0.129	.008	39	view →
LAML	DFS	Median	All	0.505	0.222	.001	38	view →
UCEC	DFS	Tertile	All	0.228	0.669	<.001	36	view →
HNSC	OS	Tertile	II,III,IV	0.132	0.423	.007	33	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	18	view →
THCA	OS	Tertile	IV	0.626	1.000	.002	18	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	18	view →
READ	OS	Tertile	All	0.286	0.727	.015	15	view →
KIRC	DFS	Tertile	II,III,IV	0.529	0.680	.046	12	view →
LGG	OS	Tertile	All	0.733	0.834	.005	12	view →
COAD	DFS	Tertile	IV	0.154	0.503	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LINC00399–LUSC (OS)

Open the LUSC breakdown →