LINC00399

Across TCGA pan-cancer cohorts, LINC00399 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC00399’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC00399 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00399 is over-expressed in tumor, although a few such as LIHC and CHOL show the opposite, repressed pattern.

LIHC, CHOL, and PRAD are the cancer types where LINC00399 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00399 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	All	−0.561	<.001	5	view →
CHOL	All	All	−0.844	<.001	3	view →
PRAD	All	All	+0.103	.003	2	view →
BRCA	All	III,IV	−0.031	.046	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LINC00399–LIHC

Open the LIHC breakdown →