LINC00396

Across TCGA pan-cancer cohorts, LINC00396 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LINC00396 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher LINC00396 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00396 expression acts as an unfavorable survival marker, although some lineages such as STAD and BRCA show a favorable association.

READ, LGG, and STAD are the cancer types where LINC00396 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.287	0.823	.001	54	view →
LGG	DFS	Median	All	0.660	0.811	<.001	53	view →
STAD	OS	Tertile	IV	0.843	0.238	.007	42	view →
HNSC	OS	Tertile	III,IV	0.284	0.689	.003	42	view →
KIRP	DFS	Tertile	II,III,IV	0.040	0.765	<.001	36	view →
UCS	DFS	Tertile	III,IV	0.116	0.441	.024	36	view →
SKCM	OS	Tertile	II,III,IV	0.093	0.373	.002	27	view →
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	18	view →
LUAD	OS	Tertile	III,IV	0.153	0.690	<.001	18	view →
BRCA	DFS	Tertile	All	0.828	0.504	.032	12	view →
CESC	OS	Tertile	III,IV	1.000	0.292	.026	12	view →
DLBC	DFS	Tertile	III,IV	0.067	0.712	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LINC00396–READ (OS)

Open the READ breakdown →