LINC00327

Across TCGA pan-cancer cohorts, LINC00327 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LINC00327 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC00327 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00327 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

UVM, ACC, and MESO are the cancer types where LINC00327 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.401	0.827	<.001	134	view →
ACC	OS	Quartile	All	0.265	1.000	<.001	57	view →
MESO	OS	Quartile	All	0.381	0.670	<.001	54	view →
KIRC	OS	Median	All	0.557	0.742	<.001	49	view →
LGG	OS	Median	All	0.728	0.887	<.001	45	view →
HNSC	DFS	Median	II,III,IV	0.386	0.267	.006	29	view →
DLBC	DFS	Median	II,III,IV	0.567	0.950	.004	20	view →
COAD	DFS	Tertile	IV	0.274	0.678	.008	20	view →
SKCM	OS	Quartile	IV	0.907	0.389	.001	18	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	18	view →
UCS	DFS	Quartile	II,III,IV	0.542	0.172	.018	14	view →
THYM	OS	Median	All	0.915	1.000	.007	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

LINC00327–UVM (DFS)

Open the UVM breakdown →