Q-omics provides the consensus-scored LINC00327 profile across patient tissues and cancer cell-line models. LINC00327 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, LINC00327 is differentially expressed in 10, with the highest sampling consensus in LUSC. Additionally, LINC00327 RNA expression shows 16,890 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and LUSC as cancer lineages where LINC00327 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00327 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00327 survival associations across molecular data types. LINC00327 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00327 RNA expression–survival associations across cancer types. High LINC00327 expression shows unfavorable associations in UVM, ACC, MESO, KIRC and LGG, but favorable associations in HNSC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for LINC00327 RNA expression.
This table summarizes LINC00327 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00327. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00327 shows lower tumor expression in LUSC, HNSC, LUAD and BRCA and higher tumor expression in KIRC and KIRP. The LUSC box plot shows higher LINC00327 RNA expression in normal versus tumor tissue (log2 FC = −0.671, t-test p < 0.001).
This table shows molecular features associated with LINC00327 in patient tissues and cancer cell lines. In patient samples, LINC00327 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
