LINC00305

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00305 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00305-associated genes across cancer lineages are RNU6-961P, IGHD5-12, and RNA5SP36. Each is linked with LINC00305 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00305-to-partner and partner-to-LINC00305 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-961P grouped by LINC00305-low versus LINC00305-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00305→partner) and Y-score (partner→LINC00305) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-961P →+0.504+8.060<.001<.00131
UCECIGHD5-12 →+1.241+6.123<.001.00231
UCECRNA5SP36 →+0.390+5.551.002.00431
UCECRN7SL132P →+0.257+5.133<.001.00831
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RNU6-961P by LINC00305 expression — UCEC

Box plot of RNU6-961P in LINC00305-low vs LINC00305-high samples in UCEC.

Explore this box plot interactively →

Exploration