LINC00305

Across TCGA pan-cancer cohorts, LINC00305 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LINC00305 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher LINC00305 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00305 expression acts as an unfavorable survival marker, although some lineages such as CESC show a favorable association.

KICH, BLCA, and HNSC are the cancer types where LINC00305 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.030	0.834	<.001	84	view →
BLCA	DFS	Tertile	II,III,IV	0.134	0.385	<.001	72	view →
HNSC	DFS	Tertile	III,IV	0.232	0.625	.002	42	view →
COAD	OS	Tertile	IV	0.185	0.670	.006	39	view →
BRCA	OS	Tertile	IV	0.220	0.822	<.001	36	view →
UCEC	DFS	Tertile	IV	0.193	0.749	<.001	36	view →
STAD	DFS	Tertile	All	0.425	0.587	.005	30	view →
ESCA	DFS	Tertile	All	0.384	0.562	.028	18	view →
THYM	DFS	Tertile	All	0.092	0.871	<.001	18	view →
MESO	OS	Quartile	All	0.244	0.604	.031	9	view →
PCPG	DFS	Tertile	All	0.637	0.878	.018	9	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

LINC00305–KICH (DFS)

Open the KICH breakdown →