LINC00299

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00299 mutation is significantly associated with the RNA expression of many other genes, with 404 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00299-associated genes across cancer lineages are SLC25A15P4, CA15P2, and NPAP1L. Each is linked with LINC00299 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00299-to-partner and partner-to-LINC00299 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A15P4 grouped by LINC00299-low versus LINC00299-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00299→partner) and Y-score (partner→LINC00299) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASLC25A15P4 →+0.430+5.045<.001.00931
BRCACA15P2 →+0.047+5.122.005.00831
BRCANPAP1L →+0.073+5.441.001.00531
BRCARNU6-1299P →+0.333+5.721.001.00331
BRCARNA5SP271 →+0.633+5.148<.001.00831
BRCARNA5SP481 →+0.278+5.441<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 404 associations by consensus.

SLC25A15P4 by LINC00299 expression — BRCA

Box plot of SLC25A15P4 in LINC00299-low vs LINC00299-high samples in BRCA.

Explore this box plot interactively →

Exploration