LINC00298

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00298 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00298-associated genes across cancer lineages are RN7SL134P, MIR548AI, and MIR6859-2. Each is linked with LINC00298 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00298-to-partner and partner-to-LINC00298 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by LINC00298-low versus LINC00298-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00298→partner) and Y-score (partner→LINC00298) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL134P →+0.212+3.599<.001.00731
UCECMIR548AI →+0.479+5.736<.001.00131
UCECMIR6859-2 →+0.824+4.105<.001.00131
UCECRNU6-173P →+0.669+4.937<.001<.00131
UCECRNY4P3 →+0.402+3.418.009.00931
UCECMIR550A1 →+0.547+3.599.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RN7SL134P by LINC00298 expression — UCEC

Box plot of RN7SL134P in LINC00298-low vs LINC00298-high samples in UCEC.

Explore this box plot interactively →

Exploration