LINC00298

Across TCGA pan-cancer cohorts, LINC00298 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC00298 data layer compared with 1 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher LINC00298 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00298 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ACC show a favorable association.

SKCM, THYM, and LUSC are the cancer types where LINC00298 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.349	0.174	<.001	72	view →
THYM	DFS	Median	All	0.643	0.855	.014	29	view →
LUSC	DFS	Quartile	III,IV	0.102	0.765	.003	28	view →
KIRC	DFS	Tertile	All	0.486	0.691	<.001	24	view →
ACC	OS	Tertile	II,III,IV	0.898	0.325	.007	21	view →
LAML	DFS	Median	All	0.471	0.657	.008	20	view →
UVM	OS	Tertile	All	1.000	0.541	.029	12	view →
READ	DFS	Tertile	IV	0.377	0.806	.005	12	view →
CESC	DFS	Median	IV	0.700	0.339	.048	6	view →
SARC	OS	Quartile	All	0.704	0.359	<.001	6	view →
ESCA	OS	Tertile	All	0.593	0.757	.011	6	view →
LUAD	DFS	Quartile	All	0.846	0.761	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC00298–SKCM (DFS)

Open the SKCM breakdown →