Across TCGA pan-cancer cohorts, LINC00265-2P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC00265-2P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC00265-2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00265-2P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
LUSC, THCA, and LUAD are the cancer types where LINC00265-2P tumor–normal differential expression is most reproducible.