LINC00251

Across TCGA pan-cancer cohorts, LINC00251 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC00251’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC00251 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00251 is over-expressed in tumor, although a few such as LIHC and ESCA show the opposite, repressed pattern.

LUAD, LIHC, and ESCA are the cancer types where LINC00251 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00251 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.114	.001	4	view →
LIHC	Female	All	−0.017	.003	4	view →
ESCA	All	All	−0.270	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC00251–LUAD

Open the LUAD breakdown →