Across TCGA pan-cancer cohorts, LINC00243 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC00243’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00243 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00243 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
HNSC, BRCA, and CHOL are the cancer types where LINC00243 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00243 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.