LINC00174

Across TCGA patient cohorts, LINC00174 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00174-associated genes across cancer lineages are SNORD116-7, RNU6-748P, and IGHD6-19. Each is linked with LINC00174 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00174-to-partner and partner-to-LINC00174 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-7 grouped by LINC00174-low versus LINC00174-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00174→partner) and Y-score (partner→LINC00174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD116-7 →	+0.657	+2.996	.001	.009	3	1
UCEC	RNU6-748P →	+0.615	+3.579	<.001	.002	3	1
UCEC	IGHD6-19 →	+0.981	+4.005	<.001	.002	3	1
UCEC	IGHD3-16 →	+1.264	+3.417	.009	.003	3	1
UCEC	IGHD2-2 →	+1.893	+4.235	.002	.001	3	1
UCEC	RNU6-821P →	+0.277	+4.260	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SNORD116-7 by LINC00174 expression — UCEC

Explore this box plot interactively →