LINC00052

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00052 mutation is significantly associated with the RNA expression of many other genes, with 702 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00052-associated genes across cancer lineages are HSP90AA6P, RWDD4, and RPL23AP82. Each is linked with LINC00052 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00052-to-partner and partner-to-LINC00052 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSP90AA6P grouped by LINC00052-low versus LINC00052-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00052→partner) and Y-score (partner→LINC00052) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHSP90AA6P →+0.785+3.519<.001.00531
UCECRWDD4 →+0.650+3.202.002.00931
UCECRPL23AP82 →+0.569+3.191<.001.00931
UCECUBE2G2 →+0.451+3.218.004.00931
UCECGP1BA →+0.367+3.218.008.00931
UCECLMNTD2 →+0.654+3.354.002.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 702 associations by consensus.

HSP90AA6P by LINC00052 expression — UCEC

Box plot of HSP90AA6P in LINC00052-low vs LINC00052-high samples in UCEC.

Explore this box plot interactively →

Exploration