LINC00052

Across TCGA pan-cancer cohorts, LINC00052 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC00052’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00052 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00052 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

HNSC, BRCA, and KIRC are the cancer types where LINC00052 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00052 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.283	.001	9	view →
BRCA	All	II,III,IV	+1.003	<.001	6	view →
KIRC	All	All	−0.181	<.001	6	view →
KIRP	All	All	−0.124	.002	5	view →
STAD	All	All	+0.023	.016	3	view →
KICH	All	II,III,IV	−0.083	.034	2	view →
LUSC	All	All	+0.063	.027	1	view →
LUAD	Female	All	+0.010	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC00052–HNSC

Open the HNSC breakdown →