LINC00052

Across TCGA patient cohorts, LINC00052 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00052-associated genes across cancer lineages are Ku80, Notch1, and p62 Lck ligand. Each is linked with LINC00052 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00052-to-partner and partner-to-LINC00052 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by LINC00052-low versus LINC00052-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00052→partner) and Y-score (partner→LINC00052) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.417	+3.013	.001	.018	3	1
UCEC	Notch1 →	+0.206	+3.169	.007	.020	3	1
UCEC	p62 Lck ligand →	+0.541	+3.009	.002	.019	3	1
UCEC	P-Cadherin →	-0.216	-2.990	.006	.036	3	1
UCEC	Caspase-8 →	-0.347	-3.143	.012	.018	3	1
UCEC	Di-Ras3 →	-0.292	-3.169	<.001	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Ku80 by LINC00052 expression — UCEC

Explore this box plot interactively →