LINC00029

Across TCGA patient cohorts, LINC00029 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,897 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00029-associated GO terms across cancer lineages are Regulation of intrinsic apoptotic signaling pathway, Extrinsic apoptotic signaling pathway via death domain receptors, and Positive regulation of DNA metabolic process. Each is linked with LINC00029 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC00029-to-partner and partner-to-LINC00029 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intrinsic apoptotic signaling pathway grouped by LINC00029-low versus LINC00029-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00029→partner) and Y-score (partner→LINC00029) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of intrinsic apoptotic signaling pathway →	+0.067	+0.116	<.001	<.001	3	14
STAD	Extrinsic apoptotic signaling pathway via death domain receptors →	+0.065	+0.100	<.001	<.001	3	13
STAD	Positive regulation of DNA metabolic process →	+0.065	+0.112	<.001	<.001	3	13
STAD	Negative regulation of transferase activity →	+0.062	+0.101	<.001	<.001	3	13
STAD	Regulation of protein serine/threonine kinase activity →	+0.056	+0.116	<.001	<.001	3	13
STAD	rRNA metabolic process →	+0.068	+0.114	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,897 associations by consensus.

Regulation of intrinsic apoptotic signaling pathway by LINC00029 expression — STAD

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