LINC-ROR

Across TCGA pan-cancer cohorts, LINC-ROR RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC-ROR’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC-ROR RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC-ROR is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

HNSC, LUSC, and BRCA are the cancer types where LINC-ROR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC-ROR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.087	.001	9	view →
LUSC	All	II,III,IV	+0.052	.009	5	view →
BRCA	Female	All	+0.026	.027	4	view →
THCA	All	All	−0.011	.003	4	view →
UCEC	All	IV	−0.075	.004	2	view →
LIHC	Female	II,III,IV	+0.075	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LINC-ROR–HNSC

Open the HNSC breakdown →