LIN7A

Across TCGA patient cohorts, LIN7A protein abundance is significantly associated with the RNA expression of many other genes, with 12,475 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LIN7A-associated genes across cancer lineages are AGTR1, ADAMTS9-AS2, and ACSS3. Each is linked with LIN7A in more than 4 cancer types. Because this analysis shows association rather than direction, both LIN7A-to-partner and partner-to-LIN7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIN7A versus AGTR1 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN7A→partner) and Y-score (partner→LIN7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AGTR1 →	+1.861	+0.729	<.001	<.001	3	5
UCEC	ADAMTS9-AS2 →	+0.906	+0.415	<.001	<.001	3	5
UCEC	ACSS3 →	+1.241	+0.419	<.001	<.001	3	5
CCRCC	ANO4 →	+1.549	+0.613	<.001	<.001	3	4
CCRCC	CSDC2 →	+1.077	+0.370	.002	.004	3	4
OV	C1QTNF1 →	+1.542	+0.731	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,475 associations by consensus.

LIN7A vs AGTR1 — BRCA

Explore this scatter interactively →