LIN37

Across TCGA patient cohorts, LIN37 protein abundance is significantly associated with the RNA expression of many other genes, with 9,037 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIN37-associated genes across cancer lineages are LIN9, VSIG4, and LINC01952. Each is linked with LIN37 in more than 4 cancer types. Because this analysis shows association rather than direction, both LIN37-to-partner and partner-to-LIN37 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIN37 versus LIN9 in LSCC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN37→partner) and Y-score (partner→LIN37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIN9 →	+0.743	+0.296	<.001	<.001	3	5
GBM	VSIG4 →	-1.045	-0.378	<.001	<.001	3	4
CCRCC	LINC01952 →	+0.617	+0.555	.001	.001	3	4
OV	LINC00638 →	+0.746	+0.961	<.001	<.001	3	4
GBM	DTL →	+1.194	+0.545	<.001	<.001	3	4
LSCC	EME1 →	+0.754	+0.333	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,037 associations by consensus.

LIN37 vs LIN9 — LSCC

Explore this scatter interactively →