LIMS1

Across TCGA patient cohorts, LIMS1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,603 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIMS1-associated genes across cancer lineages are JAM3, HSPB7, and PARVA. Each is linked with LIMS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LIMS1-to-partner and partner-to-LIMS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMS1 versus JAM3 in CCRCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMS1→partner) and Y-score (partner→LIMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	JAM3 →	+0.989	+0.323	<.001	<.001	3	8
HNSC	HSPB7 →	+1.654	+0.203	<.001	.001	3	8
GBM	PARVA →	+0.754	+0.716	<.001	<.001	3	8
UCEC	VGLL3 →	+0.892	+0.414	<.001	<.001	3	8
UCEC	LINC00702 →	+0.556	+0.428	<.001	<.001	3	8
COAD	MYL9 →	+1.356	+0.441	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,603 associations by consensus.

LIMS1 vs JAM3 — CCRCC

Explore this scatter interactively →