LIMD2

Across TCGA patient cohorts, LIMD2 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LIMD2-associated genes across cancer lineages are RNU6-79P, RNU6-97P, and RNU1-83P. Each is linked with LIMD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIMD2-to-partner and partner-to-LIMD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-79P grouped by LIMD2-low versus LIMD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMD2→partner) and Y-score (partner→LIMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-79P →	+0.455	+3.982	.005	.003	3	1
UCEC	RNU6-97P →	+0.944	+3.881	<.001	.004	3	1
UCEC	RNU1-83P →	+0.468	+3.889	.005	.004	3	1
UCEC	RNU6-969P →	+0.752	+3.867	.002	.004	3	1
UCEC	RNU6-125P →	+0.885	+3.837	.001	.005	3	1
UCEC	TRAJ31 →	+1.286	+3.971	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

RNU6-79P by LIMD2 expression — UCEC

Explore this box plot interactively →