LIMD1-AS1

Across TCGA pan-cancer cohorts, LIMD1-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LIMD1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LIMD1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LIMD1-AS1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where LIMD1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LIMD1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.663	<.001	11	view →
KIRC	Male	II,III,IV	−0.209	<.001	11	view →
LUSC	All	All	−0.147	<.001	6	view →
KICH	All	All	−0.412	<.001	4	view →
BRCA	Female	II,III,IV	−0.146	<.001	4	view →
LIHC	All	All	+0.099	<.001	4	view →
LUAD	All	III,IV	−0.146	.008	3	view →
KIRP	Male	All	−0.157	.012	2	view →
PRAD	All	All	−0.093	.014	2	view →
COAD	Female	III,IV	−0.084	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LIMD1-AS1–THCA

Open the THCA breakdown →