LIM2

Across TCGA patient cohorts, LIM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,969 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LIM2-associated GO terms across cancer lineages are Negative regulation of response to biotic stimulus, Negative regulation of leukocyte cell-cell adhesion, and Negative regulation of cell-cell adhesion. Each is linked with LIM2 in more than 14 cancer types. Because this analysis shows association rather than direction, both LIM2-to-partner and partner-to-LIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of response to biotic stimulus grouped by LIM2-low versus LIM2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIM2→partner) and Y-score (partner→LIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of response to biotic stimulus →	+0.051	+0.157	<.001	<.001	3	15
STAD	Negative regulation of leukocyte cell-cell adhesion →	+0.040	+0.125	<.001	<.001	3	14
STAD	Negative regulation of cell-cell adhesion →	+0.042	+0.164	<.001	<.001	3	14
LAML	Immune response-regulating cell surface receptor signaling pathway involved in phagocytosis →	+0.081	+0.409	<.001	<.001	3	14
STAD	Type I interferon production →	+0.054	+0.161	<.001	<.001	3	14
LAML	Positive regulation of interferon-beta production →	+0.058	+0.310	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,969 associations by consensus.

Negative regulation of response to biotic stimulus by LIM2 expression — STAD

Explore this box plot interactively →