LIM2

Across TCGA patient cohorts, LIM2 protein abundance is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LIM2-associated genes across cancer lineages are OR2A3P, C2CD4C, and RNU6-53P. Each is linked with LIM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIM2-to-partner and partner-to-LIM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIM2 versus OR2A3P in BRCA, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIM2→partner) and Y-score (partner→LIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR2A3P →	+0.095	+5.277	.002	.007	3	1
BRCA	C2CD4C →	+1.265	+5.923	.002	.001	3	1
BRCA	RNU6-53P →	+1.120	+5.277	<.001	.007	3	1
BRCA	MIR141 →	+1.205	+5.923	<.001	.001	3	1
BRCA	H2BP6 →	+0.450	+5.277	<.001	.007	3	1
BRCA	DNM3-IT1 →	+0.705	+5.923	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

LIM2 vs OR2A3P — BRCA

Explore this scatter interactively →