LIM2

Across TCGA cell cohorts, LIM2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LIM2-associated genes across cancer lineages are C16orf92, OR10Q1, and OR4F6. Each is linked with LIM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIM2-to-partner and partner-to-LIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C16orf92 grouped by LIM2-low versus LIM2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIM2→partner) and Y-score (partner→LIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C16orf92 →	+0.171	+4.037	<.001	.004	3	1
BLOOD_Leukemia	OR10Q1 →	+0.019	+4.384	<.001	.006	3	1
BLOOD_Leukemia	OR4F6 →	+0.016	+4.507	<.001	.001	3	1
BLOOD_Leukemia	OR56A3 →	+0.037	+4.060	<.001	.003	3	1
BLOOD_Leukemia	PRSS45P →	+0.059	+3.855	<.001	.007	3	1
BLOOD_Leukemia	C1orf146 →	+0.042	+3.769	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

C16orf92 by LIM2 expression — BLOOD_Leukemia

Explore this box plot interactively →