LHX9

Across TCGA patient cohorts, LHX9 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,621 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LHX9-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Obsolete regulation of ncRNA transcription, and Cellular senescence. Each is linked with LHX9 in more than 16 cancer types. Because this analysis shows association rather than direction, both LHX9-to-partner and partner-to-LHX9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by LHX9-low versus LHX9-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX9→partner) and Y-score (partner→LHX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein localization to nucleus →	+0.088	+0.120	<.001	<.001	3	17
STAD	Obsolete regulation of ncRNA transcription →	+0.076	+0.091	<.001	<.001	2	17
STAD	Cellular senescence →	+0.077	+0.126	<.001	<.001	3	14
STAD	Response to transforming growth factor beta →	+0.058	+0.083	<.001	.002	2	15
TGCT	Pharyngeal arch artery morphogenesis →	+0.080	+0.780	.001	<.001	3	13
TGCT	Negative regulation of canonical Wnt signaling pathway →	+0.053	+0.830	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,621 associations by consensus.

Regulation of protein localization to nucleus by LHX9 expression — STAD

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