Across TCGA patient cohorts, LHFPL6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,112 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LHFPL6-associated genes across cancer lineages are RPS6KL1, SUV39H1, and SLC41A2. Each is linked with LHFPL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both LHFPL6-to-partner and partner-to-LHFPL6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL6→partner) and Y-score (partner→LHFPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS6KL1 →	-1.058	-0.251	.001	.001	3	3
UCEC	SUV39H1 →	-0.704	-0.255	.002	.001	3	2
UCEC	SLC41A2 →	+1.032	+0.292	<.001	.005	3	2
LSCC	TIMP3 →	+0.943	+0.358	.001	.004	3	2
LSCC	CTSG →	+0.903	+0.391	<.001	.001	3	2
LUAD	ASPA →	+0.394	+0.214	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,112 associations by consensus.

Exploration

LHFPL6 survival (RNA) · tumor vs normal (RNA) · all LHFPL6 data types