LHFPL6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LHFPL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,833 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LHFPL6-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Maintenance of location in cell, and Regulation of mitotic sister chromatid separation. Each is linked with LHFPL6 in more than 9 cancer types. Because this analysis shows association rather than direction, both LHFPL6-to-partner and partner-to-LHFPL6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL6→partner) and Y-score (partner→LHFPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTPeptidyl-lysine oxidation →+1.068+1.690<.001<.001310
LIVERMaintenance of location in cell →+0.086+2.784.002.00139
PANCREASRegulation of mitotic sister chromatid separation →+0.093+1.451.004.00539
LUNG_NSCLC_LUSCPositive regulation of extracellular matrix organization →+0.140+2.320.001.005210
KIDNEYVentricular trabecula myocardium morphogenesis →+0.239+1.744<.001<.00139
LUNG_NSCLC_LUSCIntegrin activation →+0.222+3.337.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,833 associations by consensus.

Exploration