Across TCGA patient cohorts, LHFPL5 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,525 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LHFPL5-associated proteins across cancer lineages are SRPK1, SRPK1_S311, and TOP2A. Each is linked with LHFPL5 in more than 6 cancer types. Because this analysis shows association rather than direction, both LHFPL5-to-partner and partner-to-LHFPL5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL5→partner) and Y-score (partner→LHFPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRPK1 →	+0.473	+0.623	<.001	<.001	3	7
PDAC	SRPK1_S311 →	+0.557	+0.403	<.001	<.001	3	7
GBM	TOP2A →	+0.900	+0.479	<.001	<.001	3	7
LSCC	XPO5 →	+0.632	+0.572	<.001	<.001	3	6
LSCC	HEATR1 →	+0.336	+0.416	<.001	<.001	3	6
LSCC	UTP4 →	+0.310	+0.434	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,525 associations by consensus.

Exploration

LHFPL5 survival (RNA) · tumor vs normal (RNA) · all LHFPL5 data types