LHCGR

Across TCGA patient cohorts, LHCGR RNA expression is significantly associated with the RNA expression of many other genes, with 7,274 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LHCGR-associated genes across cancer lineages are CAVIN2, MAPK4, and ANK2. Each is linked with LHCGR in more than 13 cancer types. Because this analysis shows association rather than direction, both LHCGR-to-partner and partner-to-LHCGR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHCGR versus CAVIN2 in SARC, with a Pearson correlation of 0.25.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHCGR→partner) and Y-score (partner→LHCGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	CAVIN2 →	+1.434	+0.271	<.001	<.001	3	14
SARC	MAPK4 →	+0.718	+0.221	.001	.001	3	13
SARC	ANK2 →	+1.009	+0.256	<.001	<.001	2	14
ESCA	ADCY5 →	+1.703	+0.105	<.001	.001	3	13
ESCA	PGM5 →	+1.919	+0.151	<.001	<.001	3	13
PCPG	RGS22 →	+0.752	+0.485	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,274 associations by consensus.

LHCGR vs CAVIN2 — SARC

Explore this scatter interactively →