LGR6

Across TCGA patient cohorts, LGR6 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,137 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LGR6-associated proteins across cancer lineages are ASXL2_S1319, ATG16L2, and ATG2A_S1309. Each is linked with LGR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LGR6-to-partner and partner-to-LGR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGR6 versus ASXL2_S1319 in GBM, with a Pearson correlation of 0.80.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGR6→partner) and Y-score (partner→LGR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ASXL2_S1319 →	+0.873	+0.969	.003	<.001	3	1
GBM	ATG16L2 →	+1.055	+0.777	.001	<.001	3	1
GBM	ATG2A_S1309 →	+0.695	+0.724	<.001	<.001	3	1
GBM	ATN1_S632 →	-0.506	-1.048	.002	<.001	3	1
GBM	BAG6_S973 →	-0.853	-0.994	.004	.002	3	1
GBM	BCL7C_S122 →	-1.285	-0.838	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,137 associations by consensus.

LGR6 vs ASXL2_S1319 — GBM

Explore this scatter interactively →