LGMN

Across TCGA cell cohorts, LGMN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,025 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LGMN-associated GO terms across cancer lineages are Glycoprotein biosynthetic process, Endoplasmic reticulum to cytosol transport, and Retrograde protein transport, ER to cytosol. Each is linked with LGMN in more than 8 cancer types. Because this analysis shows association rather than direction, both LGMN-to-partner and partner-to-LGMN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycoprotein biosynthetic process grouped by LGMN-low versus LGMN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGMN→partner) and Y-score (partner→LGMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Glycoprotein biosynthetic process →	+0.053	+1.370	.002	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Endoplasmic reticulum to cytosol transport →	+0.096	+0.920	.002	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Retrograde protein transport, ER to cytosol →	+0.096	+0.920	.002	.003	3	9
SOFT_TISSUE	Protein N-linked glycosylation →	+0.081	+1.175	<.001	.001	3	9
SKIN	Membrane protein proteolysis →	+0.111	+0.747	<.001	<.001	3	9
LARGE_INTESTINE	Protein catabolic process at synapse →	+0.092	+0.927	.004	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,025 associations by consensus.

Glycoprotein biosynthetic process by LGMN expression — BONE

Explore this box plot interactively →