LGALSL

Across TCGA patient cohorts, LGALSL mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LGALSL-associated genes across cancer lineages are TMOD4, RNU6-113P, and PRR23D3P. Each is linked with LGALSL in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALSL-to-partner and partner-to-LGALSL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMOD4 grouped by LGALSL-low versus LGALSL-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALSL→partner) and Y-score (partner→LGALSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TMOD4 →	+0.029	+7.930	<.001	.008	3	1
LUAD	RNU6-113P →	+0.408	+7.930	<.001	.008	3	1
LUAD	PRR23D3P →	+0.184	+7.930	<.001	.008	3	1
BRCA	RNU6-1204P →	+0.208	+8.055	<.001	.007	3	1
UCEC	RN7SL140P →	+0.167	+4.582	.002	.005	3	1
UCEC	RN7SL366P →	+0.140	+4.582	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

TMOD4 by LGALSL expression — LUAD

Explore this box plot interactively →