LGALSL

Across TCGA pan-cancer cohorts, LGALSL RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LGALSL’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LGALSL RNA is repressed in tumor relative to normal tissue. In most cancer types LGALSL is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and COAD are the cancer types where LGALSL tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LGALSL RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−2.304	<.001	11	view →
KICH	All	III,IV	−1.325	<.001	11	view →
COAD	Female	All	−0.770	<.001	10	view →
LIHC	All	III,IV	+0.948	<.001	8	view →
KIRC	Female	All	+0.794	<.001	8	view →
THCA	All	II,III,IV	−0.603	<.001	8	view →
BRCA	All	III,IV	−0.520	<.001	6	view →
LUSC	All	All	−0.597	<.001	5	view →
CHOL	All	All	+1.352	<.001	3	view →
READ	All	All	−0.569	.002	3	view →
HNSC	All	All	−0.608	.018	2	view →
PAAD	All	All	+0.487	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LGALSL–LUAD

Open the LUAD breakdown →