LGALS9B

Across TCGA patient cohorts, LGALS9B mutation is significantly associated with the RNA expression of many other genes, with 1,227 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LGALS9B-associated genes across cancer lineages are PTP4A1P7, PGAM1P1, and RPL24P9. Each is linked with LGALS9B in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS9B-to-partner and partner-to-LGALS9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTP4A1P7 grouped by LGALS9B-low versus LGALS9B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9B→partner) and Y-score (partner→LGALS9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PTP4A1P7 →	+0.091	+3.005	<.001	.003	3	2
SKCM	PGAM1P1 →	+0.048	+3.867	<.001	.002	3	2
SKCM	RPL24P9 →	+0.120	+3.177	<.001	.001	3	2
LIHC	HMGN2P36 →	+0.135	+4.451	<.001	.006	3	2
LIHC	PIGCP2 →	+0.070	+5.305	<.001	.003	3	2
LIHC	MTCO2P21 →	+0.068	+4.648	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,227 associations by consensus.

PTP4A1P7 by LGALS9B expression — SKCM

Explore this box plot interactively →