LGALS9B

Across TCGA cell cohorts, LGALS9B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,527 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LGALS9B-associated GO terms across cancer lineages are Negative regulation of myeloid leukocyte mediated immunity, Negative regulation of mast cell degranulation, and Peptidyl-cysteine modification. Each is linked with LGALS9B in more than 9 cancer types. Because this analysis shows association rather than direction, both LGALS9B-to-partner and partner-to-LGALS9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myeloid leukocyte mediated immunity grouped by LGALS9B-low versus LGALS9B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS9B→partner) and Y-score (partner→LGALS9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of myeloid leukocyte mediated immunity →	+1.808	+0.230	<.001	<.001	3	10
KIDNEY	Negative regulation of mast cell degranulation →	+1.694	+0.227	<.001	<.001	3	10
BONE	Peptidyl-cysteine modification →	+0.124	+0.092	<.001	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of defense response to virus by host →	+0.149	+1.685	<.001	.003	3	8
LUNG_NSCLC_LUSC	Regulation of hippocampal neuron apoptotic process →	+1.689	+0.538	<.001	.005	3	7
LUNG_NSCLC_LUSC	Negative regulation of hippocampal neuron apoptotic process →	+1.596	+0.538	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,527 associations by consensus.

Negative regulation of myeloid leukocyte mediated immunity by LGALS9B expression — KIDNEY

Explore this box plot interactively →