LGALS8

Across TCGA patient cohorts, LGALS8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,345 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LGALS8-associated proteins across cancer lineages are BROX, ADSS2, and BPNT1. Each is linked with LGALS8 in more than 6 cancer types. Because this analysis shows association rather than direction, both LGALS8-to-partner and partner-to-LGALS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS8 versus BROX in UCEC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS8→partner) and Y-score (partner→LGALS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BROX →	+0.529	+0.666	<.001	<.001	3	7
LSCC	ADSS2 →	+0.462	+0.580	<.001	<.001	3	7
PDAC	BPNT1 →	+0.331	+0.304	<.001	<.001	3	5
LSCC	C1orf35 →	+0.571	+0.588	<.001	<.001	3	5
HNSC	EGLN1 →	+0.294	+0.483	<.001	<.001	3	5
LSCC	ARID4B →	+0.278	+0.558	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,345 associations by consensus.

LGALS8 vs BROX — UCEC

Explore this scatter interactively →