LGALS8

Across TCGA patient cohorts, LGALS8 protein abundance is significantly associated with the RNA expression of many other genes, with 9,904 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LGALS8-associated genes across cancer lineages are LGALS8-AS1, CD46, and KDM5B. Each is linked with LGALS8 in more than 7 cancer types. Because this analysis shows association rather than direction, both LGALS8-to-partner and partner-to-LGALS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS8 versus LGALS8-AS1 in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS8→partner) and Y-score (partner→LGALS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LGALS8-AS1 →	+0.573	+0.356	<.001	<.001	3	8
BRCA	CD46 →	+0.835	+0.335	<.001	.002	3	5
BRCA	KDM5B →	+0.621	+0.406	<.001	<.001	3	4
COAD	C1orf53 →	+0.774	+0.265	.001	.002	3	4
BRCA	LRG1 →	+2.079	+0.392	<.001	<.001	3	4
GBM	IL1R1 →	+1.191	+0.284	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,904 associations by consensus.

LGALS8 vs LGALS8-AS1 — LUAD

Explore this scatter interactively →