LGALS8

Across TCGA patient cohorts, LGALS8 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,090 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LGALS8-associated proteins across cancer lineages are ADSS2, S100A11_S6, and PDHB. Each is linked with LGALS8 in more than 5 cancer types. Because this analysis shows association rather than direction, both LGALS8-to-partner and partner-to-LGALS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS8 versus ADSS2 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS8→partner) and Y-score (partner→LGALS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADSS2 →	+0.374	+0.314	<.001	<.001	3	6
GBM	S100A11_S6 →	+0.682	+0.330	<.001	<.001	3	5
PDAC	PDHB →	-0.353	-0.157	<.001	<.001	3	5
PDAC	ETS1 →	-0.849	-0.210	<.001	<.001	3	4
LUAD	SCRN2 →	-0.263	-0.351	<.001	<.001	3	4
PDAC	NFATC2_S363 →	-0.948	-0.177	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,090 associations by consensus.

LGALS8 vs ADSS2 — LSCC

Explore this scatter interactively →